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GLUMA Desensitizer

GLUMA Desensitizer
GLUMA® Desensitizer - Under every restoration

For over 20 years, one drop of GLUMA has been sufficient to reduce and prevent hypersensitivity. The results are quick and effective, without mixing, curing or multiple applications.

Your patients feel immediate relief. Every good restoration starts with the GLUMA Desensitizer. Its efficacy has been proven in over 50 million restorations.

It can be used with all common adhesives and restoration materials and in every treatment situation. GLUMA does not need to be stirred or light cured, simplifying application and saving time.

  • Desensitize: GLUMA is the only desensitizer that has been proven to penetrate exposed dentinal tubules up to 200 μm1. This leads to the formation of multilayered protein walls which prevent an osmotic fluid exchange with the internal tubules.
  • Block bacteria: GLUMA forms a hermetic seal which traps the bacteria and prevents bacterial growth2.
  • Re-wetting: GLUMA reorganises collapsed collagen fibers and thus improves the bond strength of several adhesives.

1 Schüpbach P, Lutz F, Finger WJ: Closing of dentinal tubules by GLUMA desensitizer. Eur J Oral Sci, 1997, 105 (5Pt): 414-21
2 Felton D, Bergenholtz G, Cox CF: Inhibition of bacterial growth under composite restorations following GLUMA pretreatment. J Dent Res, 1989, 68: 491-5
For the reduction or elimination of pain in exposed cervical areas that do not require restoration and the reduction or elimination of dentin sensitivity after preparation of teeth to receive a fixed prosthesis.
Gluma Desensitizer

GLUMA Desensitizer – Step-by-step application

StepByStep

Special uses for doctors and hygiene specialists

Dentist – Under every restoration

GLUMA can be used for all direct and indirect restorations in order to give patients the comfort they deserve.
  • Under crowns
  • Bridges
  • Inlays and onlays
  • Veneers and temporary restorations.
  • Margins in the field of temporary crowns
  • Under all direct restorations

Dental Hygienists - Spot desensitization

Patients will appreciate the fast, effective and long-term results of comfortable prophylaxis through the controlled application of a gel and your trust in the GLUMA name.
  • Tooth neck erosion
  • Exposed dentine
  • Hypersensitive teeth due to gingiva recession

Scientific Evidence and Studies

Clinical Efficacy of Desensitization

Several studies for various clinical applications have been conducted to investigate GLUMA from the perspective of safety and efficacy.
GLUMA Desensitizer

Clinical efficacy - hypersensitive teeth

  • Marked reduction in post-operative pain with GLUMA dentine bonding system. 1993, Dental Practice, (Vol. 7) Reprint and translation by Bayer 1995.
  • Clinical Evaluation of GLUMA 3 Primer to Dentine Hypersensitivity. Inoue M, Yoshikawa K, Okamoto A, Kota K, Fujii B, Iwaku M. Jap J Cons Dent 1996; 39: 768-776.
  • Closing of dentinal tubules by GLUMA Desensitizer. Schupback P, Lutz F, Finger WJ. Eur J Oral Sci 1997,105: 414-421.
  • Improved efficacy of dentine-bonding agents. Hansen EK, Asmussen E. Eur J Oral Sci 1997, 105: 434-439.
  • Effect of dentine desensitizers and dentine bonding agents on dentine permeability. Jain P, Reinhardt JW, Krell KV. Am J Dent 2000, 13 (1):21–27.
  • Efficiency of Desensitizing Treatments of Hypersensitive Dentine with GLUMA and GLUMA 2000. Blunck U, Roulet JF. Internal report to Heraeus, documentation available.
  • Effectiveness of Desensitizing Agents for Dentine Hypersensitivity after Periodontal Therapy. Tenorio SB, Santos RL, Gusmao ES. J Dent Res 2002, (Special Issue B, 48:54).
  • Desensitizing effects of GLUMA and GLUMA 2000 on hypersensitive dentine. Giovanni, Dondi, Dall, Orologio G, Malferrari S. Am J Dentistry 1993, Vol 6 (no 6): 83-6.
  • Bonding to enamel and dentine: A brief history and state of the art. Swift E, Perdigao J, Heymann H. QuintIntl 1995, Vol 26 (No 2) 95–110 Special Report.


  • Clinical evaluation of GLUMA for hypersensitive root dentine (abrasion/erosion lesions). D. Davidson and Suzuki. J Dent Res 1996, 75: 364 – Abstract Nr. 2773.
  • Dentine Adhesive Materials for Restoration of Cervical Erosions. Two and Three Year Clinical Observations. Honsted-Bindslev, et. al.; Am J Dent 1998, 1:195–199, Special Issue.
  • Clinical Effectiveness of Two Agents on the Treatment of Tooth Cervical Hypersensitivity. Kakaboura A, Rahiotis, CH, Thomaidis S, Doukoudakis S. Am J Dent 2005,18: 291-295.
  • Effect of desensitizing agents on dentine permeability. Ishihata H, Kanehira M, Nagai T, Finger WJ, Shimauchi, H, Komatsu M. Am J Dent 2009, Jun 22(3): 143-6.
  • Dentine permeability reduction following application of glutaraldehyde containing desensitizer formulations. Ishihata H, Nanehira M, Finger W, Shimauchi H, Komatsu M. J Dent Res 89 (Spec Iss B), 2141, 2010.
  • Effects of two topical desensitizing agents and placebo on dentin hypersensitivity. Vora J, Mehta D, Meena N, Sushma G, Finger WJ, Kanehira M. American Journal of Dentistry, 25 (5), 2012: 293–8

Clinical efficacy - indirect restorations

  • Evaluation of the desensitizing effect of GLUMA Dentine Bond on teeth prepared for complete-coverage restorations. Felton DA, Bergenholtz G, Kanoy BE. Int’l J Prosth 1991, 4(3): 292-298.
  • Cement Thickness and Microleakage under Dicor Crowns: An In Vivo Investigation. Ferrari. Int. J Prosth 1991; 4:126–131.
  • Bonding to enamel and dentine: A brief history and state of the art. Swift E, Perdigao J, Heymann H. QuintIntl 1995, Vol 26 (No 2) 95–110 Special Report.
  • Crown Retention with use of a 5 % Glutaraldehyde Sealer on Prepared Dentine. Johnson GH, Lepe L, BaleDJ. J Prosth Dent 1998, (79: 671–6)

Effects on bond strength

  • Effect of GLUMA desensitization on dentine bond strength. Reinhardt J, Stephens N, Fortin D. Am J Dent 1995, Vol 8 (No 4) 170–172.
  • Influence of Desensitizers on Bond Strength of 2 Adhesive Systems at Dentine. Bedran de Casgtro AKB, Aramal CM, Shinohara MS, Ambrosano GMB, Pimenta LAF. J Dent Res 2002, 81: B-176.
  • Effect of GLUMA Desensitizer on Bond Strength of Etch & Rinse Adhesives. Schweppe J, Hoffmann M, Kastrati A, Utterodt A, Riedel N, Schaub M. J Dent Res 90 (Spec Issue A): 3172, 2011

Directions for use

GLUMA Desensitizer / (3002 kB) international PDF downloaden

Handling instructions

Gluma Pictorial Card / (416 kB) english PDF downloaden

Product information

Gluma Brochure / (5731 kB) english PDF downloaden

Safety Data Sheet

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Scientific information

GLUMA Desensitizer PowerGel – Clinical study I / (354 kB) english PDF downloaden
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